Chromokinesin

WebMar 3, 2003 · Kid is a kinesin-like DNA-binding protein known to be involved in chromosome movement during mitosis, although its actual motor function has not been demonstrated. Here, we describe the initial … WebJul 24, 2024 · Here, we present a novel abscission mechanism. We identified chromokinesin KIF4A, which is adjacent to the midbody during cytokinesis, as being required for efficient abscission. KIF4A is regulated by post-translational modifications. We evaluated modification of KIF4A by the ubiquitin-like protein SUMO. We mapped lysine …

Chromokinesins: multitalented players in mitosis - ScienceDirect

WebOct 8, 2024 · Chromokinesins are members of the kinesin superfamily that harbour a specific DNA-binding domain. The best characterized chromokinesins belong to the … WebSep 21, 2005 · The human chromokinesin Kid/Kinesin-10 is a plus end-directed MT-based motor ( Shiroguchi et al ., 2003; Yajima et al ., 2003) that binds both MTs and chromosomes ( Tokai et al ., 1996 ). Kid has been reported to play an important role in chromosomal movement along MTs during prometaphase and metaphase. how many grams of sugar in 8 oz orange juice https://dearzuzu.com

Chromokinesin: Kinesin superfamily regulating cell …

WebSep 21, 2011 · Interestingly, from its positioning on the chromosome arms, Hklp2 seems to restrict spindle pole separation. In the present review, we summarize the current knowledge of the function and regulation of the different kinesins associated with chromosome arms during cell division, including Hklp2 as a novel member of this so-called chromokinesin ... WebThe chromokinesins are a subgroup of kinesin motors. Chromokinesins act in various steps of mitosis, including chromosome condensation, metaphase alignment, chromosome segregation, cytokinesis and they help maintain genome stability. WebAug 23, 2004 · Chromokinesins represent a family of chromosome arm-binding kinesins consisting of two distinct types of members: chromokinesins/KIF4 and the Kid … hovis warrington

Fe-S cluster coordination of the chromokinesin KIF4A alters its ...

Category:Mitotic DNA damage promotes chromokinesin-mediated …

Tags:Chromokinesin

Chromokinesin

Chromokinesin Kid and kinetochore kinesin CENP-E

WebSep 30, 2013 · Here we show that a quantum dot (Qdot) binding up to four Xenopus chromokinesin (Xkid) molecules behaved like a nanosize chromosome arm in the … WebSep 1, 2016 · As a vital kind of kinesin, chromokinesin functions in different kinds of cells and organisms, from nerve cells to germ cells, from Drosophila to human. We have …

Chromokinesin

Did you know?

WebJun 27, 2024 · The chromokinesin KIF4A associates with microtubules and contributes to chromosome segregation during mitosis. Here, we show that this function depends on a …

WebJul 1, 2005 · Download : Download full-size image Figure 1. Molecular structure and cellular localization of chromokinesins. (a) Schematic domain structure of Kinesin-4 and Kinesin-10.(b) Localization of chromokinesin HKIF4A and effects on mitosis upon its loss. (top row) Human KIF4A localizes to the nucleus during interphase, associates with mitotic … WebSep 30, 2013 · Here we show that a quantum dot (Qdot) binding up to four Xenopus chromokinesin (Xkid) molecules behaved like a nanosize chromosome arm in the meiotic spindle, which is self-organized in ...

WebThe chromokinesin KIF22 (Kid, kinesin-10 family) is the primary generator of polar ejection forces, which contribute to chromosome positioning and alignment in mitotic cells. Assessment of KIF22 function requires quantitative comparison of relative polar ejection forces between experimental conditions. This is facilitated by the generation of ... WebApr 11, 2024 · This delay was due to the presence of misaligned chromosomes that ultimately satisfy the SAC and missegregate, leading to micronuclei formation. Mechanistically, it is shown that mitotic DNA damage causes missegregation of polar chromosomes due to the action of arm-ejection forces by chromokinesins.

WebOct 3, 2003 · Mitosis requires the concerted activities of multiple microtubule (MT)-based motor proteins. Here we examined the contribution of the chromokinesin, KLP3A, to mitotic spindle morphogenesis and chromosome movements in Drosophila embryos and cultured S2 cells. By immunofluorescence, KLP3A associates with nonfibrous punctae that …

WebOct 8, 2024 · Chromokinesins are members of the kinesin superfamily that harbour a specific DNA-binding domain. The best characterized chromokinesins belong to the … hovis wheatgerm 400gWebMar 6, 2015 · The chromokinesin Kid is necessary for chromosome arm orientation and oscillation, but not congression, on mitotic spindles. J. Cell Biol. 154 , 1135–1146 (2001) . hovis wheatgermWeb开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 hovis whiteWebWe previously reported on the experimental validation of several in silico-predicted glioma biomarkers (e.g., Plexin-B2 (PLXNB2), SLIT3, and Spondin-1 (SPON1)) that were found to be higher in human high-grade gliomas (HGGs). In this study, we validated their therapeutic potential by investigating antibody therapies against these three biomarkers in a … hovis wheatgerm bread tescoWebJul 1, 2008 · Chromokinesins are microtubule-motor molecules that possess chromatin binding activity and are important for mitotic and meiotic regulation. The chromokinesin-member Kif4A is unique in that it localizes to nucleus during interphase of the cell cycle. Kif4 deletion by gene targeting in mouse embryoni … how many grams of sugar in 1 sugar packetWebOct 8, 2024 · Chromokinesins are members of the kinesin superfamily that harbour a specific DNA-binding domain. The best characterized chromokinesins belong to the kinesin-4/Kif4 and kinesin-10/Kif22 … how many grams of sugar in a cinnabonWebJul 24, 2024 · (A) Chromokinesin KIF4A is required for the positioning of mitotic chromosomes and stabilization of the bipolar spindle. In cytokinesis, KIF4A localizes at … hovis white cob